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HIGHLIGHTS

Burns L, Giannakopoulou N, Zhu L, Xu YZ, Khan RH, Bekal S, Schurr E, Schmeing TM, Gruenheid S. The bacterial virulence factor NleA undergoes host-mediated O-linked glycosylation. Mol Microbiol 2022.

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Cannon T, Sinha A, Trudeau LE, Maurice CF, Gruenheid S. Characterization of the intestinal microbiota during Citrobacter rodentium infection in a mouse model of infection-triggered Parkinson's disease. Gut Microbes 2020.

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Matheoud D*, Cannon T*, Voisin A, Penttinen AM, Ramet L, Fahmy AM, Ducrot C, Laplante A, Bourque MJ, Zhu L, Cayrol R, Le Campion A, McBride HM*, Gruenheid S*, Trudeau LE*, Desjardins M*. Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice. Nature 2019.

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Kang E, Zhou G, Yousefi M, Cayrol R, Xia J, Gruenheid SLoss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses. Sci Rep 2018.

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Graphical abstract of "Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice" Nature paper.

 

Thomassin JL, Leclerc JM, Giannakopoulou N, Zhu L, Salmon K, Portt A, Daigle F, Le Moual H, Gruenheid SSystematic Analysis of Two-Component Systems in Citrobacter rodentium Reveals Positive and Negative Roles in Virulence. Infect Immun 2017.

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Kang E, Yousefi M, Gruenheid SR-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice. PLoS One 2016.

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Thomassin JL, Giannakopoulou N, Zhu L, Gross J, Salmon K, Leclerc JM, Daigle F, Le Moual H, Gruenheid SThe CpxRA two-component system is essential for Citrobacter rodentium virulence. Infect Immun 2015.

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Papapietro O, Teatero S, Thanabalasuriar A, Yuki KE, Diez E, Zhu L, Kang E, Dhillon S, Muise AM, Durocher Y, Marcinkiewicz MM, Malo D, Gruenheid SR-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nat Commun 2013.

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